Money is power, and without it, life is meaningless. In a country whose economy is in shambles, second-year economics university student Kimimaro Yoga understands this fact all too well, as he is surrounded by the relatively luxurious lives of his peers and struggling to make ends meet. However, his world is turned on its head when a stranger in a top hat arrives one late night at his door. Going by the name Masakaki, the visitor petitions Yoga to come to the Eastern Financial District, a place where money flows in abundance if one offers their "future" as collateral. Although reluctant, greed triumphs reason and Yoga accepts the offer, thus taking on the mantle of an Entre. But unbeknownst to him, the land of wealth he has entered is an alternate realm built in the likeness of his own, where Entres are forced to participate in weekly duels called Deals, with their collateral at stake. Pitted against his countrymen and fate, Yoga must quickly adapt in this new world if he hopes to protect his fortune and future—and discover just how much money is truly worth.

Lucy is a special breed of human referred to as "Diclonius," born with a short pair of horns and invisible telekinetic hands that lands her as a victim of inhumane scientific experimentation by the government. However, once circumstances present her an opportunity to escape, Lucy, corrupted by the confinement and torture, unleashes a torrent of bloodshed as she escapes her captors. During her breakout, she receives a crippling head injury that leaves her with a split personality: someone with the mentality of a harmless child possessing limited speech capacity. In this state of instability, she stumbles upon two college students, Kouta and his cousin Yuka, who unknowingly take an injured fugitive into their care, unaware of her murderous tendencies. This act of kindness will change their lives, as they soon find themselves dragged into the shadowy world of government secrecy and conspiracy.

Ai Enma and her companions continue to offer their service of revenge against those who have wronged others, and the price is as steep as ever—for damning the offender to hell, the person exacting vengeance is sent to the abyss as well. As they cast soul after soul into the darkness, a new sinister force is watching them: a little girl named Kikuri. While Ai continues her duties, she meets a boy named Takuma Kurebayashi, known as the "Devil's Child" because of the horrific events that occur around him. Unfortunately, Takuma's reputation leads the townspeople to use him as a scapegoat for those who have been ferried off to hell. When things quickly spiral out of control, Ai must find a way to bring an end to this senseless violence, as it poses a threat to her very existence.