When tragedy is about to strike, Satoru Fujinuma finds himself sent back several minutes before the accident occurs. The detached, 29-year-old manga artist has taken advantage of this powerful yet mysterious phenomenon, which he calls "Revival," to save many lives. However, when he is wrongfully accused of murdering someone close to him, Satoru is sent back to the past once again, but this time to 1988, 18 years in the past. Soon, he realizes that the murder may be connected to the abduction and killing of one of his classmates, the solitary and mysterious Kayo Hinazuki, that took place when he was a child. This is his chance to make things right. Boku dake ga Inai Machi follows Satoru in his mission to uncover what truly transpired 18 years ago and prevent the death of his classmate while protecting those he cares about in the present.

After unknowingly participating in a kidnapping, college student Yuuya Nomoto finds his friends brutally murdered by Hitomi Uzaki, the high school girl they attempted to abduct. Forced to drive her to an undisclosed location, he finds himself being wagered as the prize for a death match between two Therianthropes, superpowered human-animal hybrids created through advanced gene therapy. As one of these hybrids, Hitomi uses the speed and fearlessness she gained from her ratel genes to viciously dispatch her foe and save Yuuya from certain death. Waking up hours later hoping the whole event was only a nightmare, Yuuya realizes that he has become embroiled in a secret proxy war between four large Japanese business conglomerates, with the winner taking control of the economy. As her sole albeit unwilling investor, his life is now directly linked to Hitomi's ability to participate in underground bloodsport matches known only as Killing Bites.

A blog disproving the supernatural, co-run by NEET teenager Yuuta Gamon and his enthusiastic best friend Ryouka Narusawa, becomes the catalyst that would bring together a group of people who supposedly have nothing to do with each other. These individuals include high school fortune teller Miyuu Aikawa, who joins Yuuta to work on the blog; realist Sarai Hashigami, who is stunned when tragedy strikes his family; doujin artist Ririka Nishizono, who has an uncanny ability to predict the future with her art; black magic practitioner and local curse expert Aria Kurenaino and her ghostly friend; Shun Moritsuka, a seemingly childish otaku detective; and reporter Touko Sumikaze. As this unlikely group, bound only by the strings of fate, find their way to each other, they are confronted with murder and other events that are shrouded by the presence of the supernatural. They must band together to solve the mysteries interlacing the city and their lives.

People fall in love in the most mysterious of ways. This statement seems to be especially true for the affluent genius playboy Ryou Amakusa. When he nearly falls off the stairs one rainy morning, a girl named Ichika Arima saves him. As if by fate, Ryou encounters Ichika again later that night; she happens to be the best friend of his little sister, Rio. Wanting to "thank" her, Ryou attempts to woo Ichika by employing his usual flirtatious tactics only to be immediately shot down, his target creeped out by his behavior. Rather than being discouraged, Ryou instead becomes more enthralled by her, and he begins to do everything he can to steal Ichika's heart despite receiving disgusted reactions each time. However, as time passes by, will Ichika remain repulsed by Ryou's creepy yet dedicated advances?