When Isaku Senagaki was five years old, the death of her parents left her to be raised by her yakuza boss grandfather, Tasuke. Now preparing to enter high school, Isaku is determined to start fresh with an honest attempt at having a normal high school experience. All she wants is to be able to make friends and find love without being defined by her connection to the yakuza. But Isaku's dreams are thwarted when her overprotective caretaker, 26-year-old Keiya Utou, takes it upon himself to enroll in Isaku's school by bribing the school administration. While Isaku yearns for a reciprocated love, she is trapped in a one-sided infatuation with Keiya, who only sees her as the boss's granddaughter he helped raise. Her longing for a normal life becomes a constant battle, and breaking free from her heart's grip is far more challenging than it sounds, as Keiya's overprotectiveness and disregard for her boundaries make it almost impossible to move on.

High schooler Ganta Nakami has trouble falling asleep most nights. As a result, he is irritable at school, always searching for an opportunity to find a secluded place to doze off. On the other hand, Isaki Magari is a free spirit who is well liked by her friends, but no one is aware of her sleep disorder. She makes use of the school's abandoned astronomy club observatory as her secret sleeping bunker when she needs to get some shut-eye. As fate would have it, Nakami finds Magari napping in the observatory. When Magari discovers that she and Nakami have something in common, she offers to share her secret sleeping spot with her fellow insomniac. As the two find warmth in each other's company, the struggles they face start to become easier to confront.

Spirits have always been attracted to Keitarou Gentouga due to his strong spiritual presence. A traumatic encounter with one had caused his right hand to be cursed, forcing him to wear a glove at all times. Now a college freshman, Keitarou is trying to live as normal a life as possible. With the encouragement of his childhood friend Eiko Houzuki, he becomes a private tutor. Since he is at the top of his intake class, his first client is the tutoring firm's most promising student, Yayoi Houzuki. To Keitarou's surprise, Yayoi is Eiko's cousin, and she possesses two pupils in each eye—allowing her to see into the spirit world and purposely seek vengeful spirits to exorcise. Ever since a car accident killed both her parents, Yayoi has been searching for the powerful spirit that kidnapped her mother's departed soul. Seeing that spirits are so attracted to Keitarou, she ropes him into helping her collect other evil spirits that will assist in her future fight. Although her quest is dangerous, Keitarou reluctantly decides to join her, even as each new spirit they meet has him questioning his resolve at every turn.

The happy-go-lucky Michi Sonoda announces to her teammate, Sanae Takigawa, that she will quit judo for good after her final middle school tournament. This leaves Sanae in disbelief; after all, it was Michi's passion toward the sport that reeled Sanae into judo in the first place. Michi claims that a well-spent youth should be associated with things such as getting a boyfriend rather than sweaty tatami mats. However, Michi's plan to end her fledgling judo career with a bang is spoiled after experiencing an embarrassing defeat at the hands of the talented Towa Hiura. Later, her plan is further derailed when she finds out that Towa has enrolled in the same high school as herself and Sanae. With the sudden appearance of her past foe, Michi may soon realize that she still has lingering feelings for the sport of judo.