Shoujo-tachi wa Kouya wo Mezasu is a series all about finding oneself and a direction in life... no matter how far off the beaten path it might be. Buntarou Hojo is a high school student who has a talent for writing, but no real direction in life or any plans for the future. His classmate, Sayuki Kuroda notices his talent, decides to help him find a way to use it properly by enlisting him in her bishoujo game development group. When Buntarou is cornered in the men's bathroom at school by Sayuki, he is surprised when he is asked out on what he thinks is a date, and even further surprised when he finds out that it's not a date, but a job interview. Reluctantly agreeing, the two start recruiting other members for their team but will they learn more about game creation, or life itself along the way?

Fumizuki Academy isn't a typical Japanese high school. This unique institution has implemented a new and innovative system to sort its students. At the end of their freshman year, students take a test that divides up the student body. The highest scorers are placed into A class, all the way down until F class, for the lowest of the low. Unfortunately for Akihisa Yoshii, his supposedly "great" intellect wasn't quite enough for such a test, and he's now stuck at the bottom of F class. Naturally, F class has the worst facilities: not only rotten tatami mats and broken tables, but also outdated equipment and worn out furniture. On the bright side, his friend Yuuji Sakamoto is in the same class, and to everyone's surprise, the genius girl Mizuki Himeji has also ended up in the same class due to an unforeseen fever on the day of the test. Unsatisfied with their perquisites, F class rallies behind Yuuji, determined to take on the higher-tiered classes in order to seize their perks by using the school's Examinations Summon Battle system. The participants can summon fantasy characters—whose power levels are equal to their student's test scores—in an all-out battle. Will F class be able to rise to the top, or will they live up to everyone's expectations and fail?

The blockheads of Class F return with more misadventures! Rather than desperately competing against the elite students in Class A for better facilities, they have other problems at hand. While the girls are constantly vying for the boys' attention, Akihisa Yoshii and Yuuji Sakamoto are being blackmailed by a stalker who threatens to reveal their most embarrassing secrets to the whole school. Moreover, everyone's avatar starts to behave strangely. Filled with more nosebleeds and eye-pokes, the boys of Class F must work together to discover the stalker's identity and deal with the misfortunes that come with love among fools.

For many girls in N-City, playing the popular social role-playing game Magical Girl Raising Project is as close as they could come to being a real magical girl. However, for some rare players, that dream can become a reality. One such girl is Koyuki Himekawa, who receives a notification one night that she has been selected to become a magical girl, her in-game avatar Snow White. As Koyuki and other chosen players in the city begin helping those in need, they all receive yet another notification: the admins have decided that they want to reduce the number of magical girls. Whoever collects the least amount of Magical Candies—which are awarded for their magical girl activities—in their competition each week will lose their powers. But when a real-world tragedy happens to the first player that drops out, they are shown the repercussions of losing their abilities. As more participants inevitably lose the competition and more twisted rules are added, the girls soon realize that their "contest" is actually a desperate fight for survival.