For weeks, Atsushi Nakajima's orphanage has been plagued by a mystical tiger that only he seems to be unaware of. Suspected to be behind the strange incidents, the 18-year-old is abruptly kicked out of the orphanage and left hungry, homeless, and wandering through the city. While starving on a riverbank, Atsushi saves a rather eccentric man named Osamu Dazai from drowning. Whimsical suicide enthusiast and supernatural detective, Dazai has been investigating the same tiger that has been terrorizing the boy. Together with Dazai's partner Doppo Kunikida, they solve the mystery, but its resolution leaves Atsushi in a tight spot. As various odd events take place, Atsushi is coerced into joining their firm of supernatural investigators, taking on unusual cases the police cannot handle, alongside his numerous enigmatic co-workers.

Despite their differences in position, three men—the youngest senior executive of the Port Mafia, Osamu Dazai; the lowest ranking member, Sakunosuke Oda; and the intelligence agent, Ango Sakaguchi—gather at the Lupin Bar at the end of the day to relax and take delight in the company of friends. However, one night, Ango disappears. A photograph taken at the bar is all that is left of the three together. Fast forward to the present, and Dazai is now a member of the Armed Detective Agency. The Guild, an American gifted organization, has entered the fray and is intent on taking the Agency's work permit. They must now divide their attention between the two groups, the Guild and the Port Mafia, who oppose their very existence.

Mitsuha Miyamizu, a high school girl, yearns to live the life of a boy in the bustling city of Tokyo—a dream that stands in stark contrast to her present life in the countryside. Meanwhile in the city, Taki Tachibana lives a busy life as a high school student while juggling his part-time job and hopes for a future in architecture. One day, Mitsuha awakens in a room that is not her own and suddenly finds herself living the dream life in Tokyo—but in Taki's body! Elsewhere, Taki finds himself living Mitsuha's life in the humble countryside. In pursuit of an answer to this strange phenomenon, they begin to search for one another. Kimi no Na wa. revolves around Mitsuha and Taki's actions, which begin to have a dramatic impact on each other's lives, weaving them into a fabric held together by fate and circumstance.

Death does not have to be the end; one can live again, but only through beating the game posed by the black ball called Gantz. On his way home to celebrate his younger brother's birthday, brave and kind-hearted student named Masaru Katou is stabbed to death. He awakes in a small room with a cityscape view in the heart of Tokyo—and he is not alone. To his surprise, it is not the afterlife, but the waiting room for a high stakes game with their lives on the line. Before he has the chance to process the situation, Masaru is handed a gun and teleported into the center of Osaka to carry out one simple task: eliminate any alien on sight. Accompanied by the aged Yoshikazu Suzuki, the stunning idol Reika Shimohira, and the cold but experienced Jouichirou Nishi, Masaru must overcome his fears in order to survive the game and return home to his waiting brother.