There is a tower that summons chosen people called "Regulars" with the promise of granting their deepest desires. Whether it be wealth, fame, authority, or something that surpasses them all—everything awaits those who reach the top. Twenty-Fifth Bam is a boy who had only known a dark cave, a dirty cloth, and an unreachable light his entire life. So when a girl named Rachel came to him through the light, his entire world changed. Becoming close friends with Rachel, he learned various things about the outside world from her. But when Rachel says she must leave him to climb the Tower, his world shatters around him. Vowing to follow after her no matter what it takes, he sets his sight on the tower, and a miracle occurs. Thus begins the journey of Bam, a young boy who was not chosen by the Tower but opened its gates by himself. They call his kind "Irregulars"—beings that have shaken the very foundation of the Tower each time they set foot inside it.

Tired of being looked down upon for her unattractive appearance, middle schooler Lim Jugyeong turns to the transformative powers of makeup. First, she experiments with BB cream, lip tint, and eyeliner; then she begins using mascara, double eyelid glue, and colored contacts. Before she knows it, Jugyeong goes from being a girl who is bullied for her ugliness to being praised as a high-class beauty. Constantly surrounded by those who adore her goddess-like appearance, Jugyeong can now live a more than comfortable life at school—she simply has to keep her bare face a secret. However, everything changes when the new transfer student, Lee Suho, enters her life. Not only does the handsome Suho become immediately popular among their peers, but in a chance encounter, he also becomes the only classmate of Jugyeong's to see her face beneath the makeup. With her reputation on the line, Jugyeong must do whatever it takes to hide the truth about her appearance from the rest of her classmates. But the more time she spends with Suho, the more Jugyeong finds herself questioning whether one's true beauty lies solely in their looks.

The "Noblesse" Cadis Etrama di Raizel, also known as "Rai," is enrolled in Ye Ran High School by his servant Frankenstein to stay hidden from the sights of the Union, a mysterious organization out for Rai's blood. Rai commences his life as a student, making himself familiar with his classmates and the daily activities of humans. However, his new life is far from peaceful, and Rai is soon forced to save his new friends from the hands of the Union that had abducted them. Meanwhile, M-21—a Union agent gone rogue during Rai's rescue operation—joins the Ye Ran High School security staff after a proposition by the school's director, who happens to be none other than Frankenstein himself. On the surface, M-21 is a prim and proper employee, but in truth he is shackled by his former ties to the Union and the inevitable consequences of betraying the organization. To further complicate matters, Nobles Regis K. Landegre and Seira J. Loyard enroll in the same school to investigate the Noblesse. While the Union conducts a manhunt for M-21 to extract clues regarding their missing agents, Rai is forced to keep his identity hidden while protecting all that he holds dear.