After her battle against the mysterious organization Amarariruku, Teru Momijiyama returns to her regular life in Tokyo—all while secretly continuing to save people as Japan's hero Shy. As a result of her experiences with others, Teru is able to slowly gain confidence in herself. While she still has a long way to go, Teru continues to make progress towards learning what being a hero truly means. While walking around the city after school, Teru runs into Ai Tennouji, whom she quickly befriends and begins to open up toward. Teru quickly learns more about her new friend’s past—she has run away from her village in search of something directly related to Teru's work as Shy. While the threat of Amarariruku continues to loom over her,Teru must decide how closely she is willing to work with the mysterious Ai.

Vampires are known to have many weaknesses that balance out their incredible power, but the vampire lord Draluc happens to be weak to pretty much anything. The vampire hunter Ronald receives a job to infiltrate the castle of the so-called "Invincible Progenitor" and rescue a woman's son from the monster within. But upon arriving, he is dumbfounded to discover that the vampire quickly turns to ash by something as trivial as a clap of his hands! Moreover, the child he was sent to save had merely wandered in to play the vampire lord's video games while he slept! In a disastrous turn of events, Draluc's castle is destroyed, and the fragile vampire decides to move in with the hunter who has only just defeated him. Ronald, Draluc, and the vampire's pet armadillo John form quite the eccentric team as they are forced to work together while fending off Ronald's violent editor, the lesser vampires plaguing the city, and even their fellow vampire hunters.