Three sisters, Hozuki, Kazuki, and Hazuki, are descendants of Galileo and have completely different personalities and tastes; they never meet eye-to-eye. One day, the girls are suddenly attacked by a mysterious organization. The organization was after the "Galileo Tesoro" which Galileo Galilei was said to have discovered. Still unaware of what was going on, the sisters escape on the airship they built after the sudden attack. But it won't be so easy for these three sisters to help each other out in a pinch when they're constantly at odds with each other. What is the Tesoro, and what is the organization after? And what about the relationship between the sisters? It's a threesome of cute girls, action, and mystery! (Source: Fuji Creative)

After Germania invaded a neighboring country in 1939, Europe spiraled into a devastating war. During the war, Germania set its sights on the weak alpine country of Elystadt. Boasting a far superior military and having achieved profuse success earlier in the war, it was expected that Germania would conquer Elystadt with ease. Matters are only made worse for the small country when Germanian soldiers capture their princess, Ortfiné "Finé" Fredericka von Eylstadt, as she is heading to a crucial meeting with Britannia. Yet, when a concurrent Germanian transport mission goes awry, Izetta, the last witch alive, escapes. When she recognizes Princess Finé from her childhood, Izetta rescues her from the Germanian soldiers by making use of her magical abilities. Now reunited with the princess, Izetta pledges to protect Elystadt from Germania, and with the last surviving witch on their arsenal, Elystadt hopes to turn the tides against the imperialist war giant.

Middle school students Nagisa Misumi and Honoka Yukishiro are the epitome of dissimilarity. Popular with their classmates, Nagisa is the school's energetic star lacrosse player, while Honoka is the soft-spoken "Queen of Intelligence." As unrelated as they may seem, Nagisa and Honoka live double lives as the "emissaries of light": Cure Black and Cure White of Pretty Cure. With the assistance of two fairies, Mipple and Mepple, the girls fight against the Dotsuku Zone—an evil force that has invaded the Garden of Light. In order to prevent the Dotsuku Zone from taking over the Garden of Rainbows as well, the pair must work together to find seven Prism Stones and restore the Prism Hopish to drive out the vile forces. With strong foes standing in their way, Nagisa and Honoka learn to work together and harness their newfound powers in order to save the worlds from further ruin.

Iroe Genma is a third-year high school student often referred to as "Elder Sister" despite her short height. This troublemaking teenager is the president of her school's Model Club, which is dedicated to building plastic models of various objects and structures, such as cars, boats, and even robots. Joined by her two underclassmen, the violent Hazuki "Okappa" Okamoto and the rational Makina "Makimaki" Sakamaki, the small group aims to carry out their club duties but are often sidetracked by a myriad of distractions. From battles between club members to lessons on how to confess to your crush, these three schoolgirls get caught up in all sorts of wacky, and downright outrageous situations!