The animals of Third Street are seen getting into many misadventures. Tama Okamoto, the curious feline, often goes missing from his home, causing his owner to have posters up looking for him. However, Tama's absence is his opportunity to visit all of his wandering furry friends around the neighborhood. From Tama's best friend Pochi Yamada to the stray alley cat Nora, these animals take human form to hang out, to cause various mischief, but most of all, to have fun!

The world has been engulfed in a desperate, three-decade-long war against the BETA—an alien species that invaded the planet in 1973. Amid this chaos, a high school student named Takeru Shirogane suddenly wakes up from a terrifying nightmare where he sees mankind in utter defeat. Soon after, he realizes that his dream was nothing more than the recollections of his life in an alternative universe. In those memories, the Alternative V project is implemented, sending hundreds of thousands of people into space as a last resort to preserve humanity, while leaving the remaining billion on Earth to suffer a cruel fate. Yearning to change this grim future, Takeru joins a military base in Yokohama, which happens to be his former high school. There, he manages to convince the base's vice-commander and leader of the Alternative IV project, Professor Yuuko Kouzuki, to prevent Alternative V from happening. To ensure the success of Alternative IV, Takeru must pilot the gigantic humanoid machines Tactical Surface Fighters (TSF) alongside his fellow cadets. However, he has only two months to complete his training and exploit his partial knowledge of the future—lest the ensuing tragedy take place.

Genius setter Kimichika Haijima moves back to Fukui from Tokyo after an incident within his school's volleyball team forces him out. There, he is reunited with his childhood friend, Yuni Kuroba, a member of the Monshiro Middle School Boys' Volleyball Team, who is unaware of his own talents. Haijima notices Kuroba's abilities and is determined to form a new volleyball team with Kuroba as the team's ace. At the prefectural tournament, Kuroba crumbles under the pressure, which causes the Monshiro team to fall apart after losing. The loss also creates a rift between Haijima and Kuroba, leading the former to quit the team. Now, as students at Seiin High School, Haijima and Kuroba find themselves on the same volleyball team once again. Having learned from his past mistakes, Haijima helps Kuroba overcome his performance anxiety to become the ace and carry the team to the prefectural championship. With support from team captain Shinichirou Oda and vice captain Misao Aoki, Seiin aim to win the prefecturals and become Fukui's representatives at the Spring Tournament. To do this, they will need to beat Fukuho Technical High School, the reigning champions of Fukui. Will Haijima's team defeat the odds, or are they doomed to repeat his history of losing?

Daisuke Kanbe, a man of extraordinary wealth, is assigned to the Modern Crime Prevention Headquarters as a detective. It is there that he gets partnered with Haru Katou, a humane detective who values justice above all. The two are polar opposites, and their morals clash time and time again. Haru despises Daisuke for using monetary wealth to solve cases, as he believes that money isn't everything. The two will have to combine their efforts, however, to solve the mysteries that are coming their way.