Ron Kamonohashi, the best student in the history of the elite Detective Training Academy BLUE, has been living as a recluse since BLUE expelled him five years ago. Moreover, he is forbidden to work as a detective, having barely escaped execution after getting involved in a murder case while he was still attending the school. Ron's situation changes drastically when police detective Totomaru Isshiki, following the advice of a senior colleague, seeks him out for help with a criminal case that has remained unsolved for months. Ron reluctantly agrees to help Totomaru and uses his phenomenal intuition to discover the culprit in less than a day. However, it appears that Ron suffers from a mysterious condition that can cause those around him to lose their lives. To Ron's great surprise, Totomaru manages to save the life of someone whom Ron put in jeopardy. As the unlikely duo starts solving crimes one after another, BLUE sends operatives after its former student to find out if he has resumed investigative work. Fighting against murderers, rogue detectives, and the Metropolitan Police Department, Ron and Totomaru must join forces if they want to survive and see justice prevail.

Yuuta Takemoto, a sophomore at an arts college, shares a cheap apartment with two seniors—the eccentric Shinobu Morita, who keeps failing to graduate due to his absenteeism, and the sensible Takumi Mayama, who acts as a proper senior to Takemoto, often looking out for him. Takemoto had not given much thought to his future until one fine spring day, when he meets the endearing Hagumi Hanamoto and falls in love at first sight. Incredibly gifted in the arts, Hagumi enrolls in Takemoto's university and soon befriends the popular pottery student Ayumi Yamada. Ayumi is already well acquainted with the three flatmates and secretly harbors deep feelings for one of them. Hachimitsu to Clover is a heartwarming tale of youth, love, soul-searching, and self-discovery, intricately woven through the complex relationships between five dear friends.

Back from his journey across Japan, Yuuta Takemoto reminisces about his college life so far. He has matured significantly since his second year and is motivated to move forward. Feeling more confident than ever before, he finally confesses to Hagumi Hanamoto, the girl he has been in love with since their first encounter. However, Hagumi has been confused by her attempts to understand the mysterious Shinobu Morita. Hiding behind a playful demeanor, Morita may be the most burdened by his own potential. Meanwhile, Takumi Mayama has become a full-fledged working adult and has landed Ayumi Yamada several pottery orders through his company in an act of friendship. The five youths continue to face individual hardships in academics, work, love, and friendship as they push each other toward the paths that they are destined to walk.

Ichigo Kurosaki is an ordinary high schooler—until his family is attacked by a Hollow, a corrupt spirit that seeks to devour human souls. It is then that he meets a Soul Reaper named Rukia Kuchiki, who gets injured while protecting Ichigo's family from the assailant. To save his family, Ichigo accepts Rukia's offer of taking her powers and becomes a Soul Reaper as a result. However, as Rukia is unable to regain her powers, Ichigo is given the daunting task of hunting down the Hollows that plague their town. However, he is not alone in his fight, as he is later joined by his friends—classmates Orihime Inoue, Yasutora Sado, and Uryuu Ishida—who each have their own unique abilities. As Ichigo and his comrades get used to their new duties and support each other on and off the battlefield, the young Soul Reaper soon learns that the Hollows are not the only real threat to the human world.