The second part of Nanbaka. The prisoners and their guards continue their comfortable lives at Nanba Prison. However, from the shadows emerges a new threat: Enki Gokuu, a person from Samon's past, who has mysterious goals of his own.

Since childhood, Aoba Suzukaze has loved the Fairies Story game series, particularly the character designs. So when she graduates from high school, it is no surprise that she applies to work at Eagle Jump, the company responsible for making her favorite video game. On her first day, she is excited to learn that she will be working on a new installment to the series: Fairies Story 3—and even more so under Kou Yagami, the lead character designer. In their department are people who share the same passion for games. There is Yun Iijima, whose specialty is designing monsters; the shy Hifumi Takimoto, who prefers to communicate through instant messaging; Hajime Shinoda, an animation team member with an impressive figurine collection; Rin Tooyama, the orderly art director; Shizuku Hazuki, the game director who brings her cat to work; and Umiko Ahagon, the short-tempered head programmer. New Game! follows Aoba and the others on their adventure through the ups and downs of game making, from making the perfect character design to fixing all the errors that will inevitably accumulate in the process.

​It has been a year since Aoba Suzukaze started working at the Eagle Jump game company. In that time, she and her eccentric coworkers in the character design department have worked hard to release the company's newest game: Fairies Story 3. With their latest title now complete, a new project must begin—starting with a contest to decide the character designs for the upcoming game. Through hard work, dedication, and some guidance from the previous character designer, Kou Yagami, Aoba wins the contest and begins her new role as lead character designer. However, her new job is not an easy one. In addition to having extra work and longer hours, Aoba questions whether she is the right fit for the job. As she overcomes her inexperience with the help of her friends and coworkers, Aoba is willing to face any challenge to make Eagle Jump's newest creation, a cutesy game called Peco.

Hotaru Ichijou's lifestyle completely changes when she leaves Tokyo and moves with her family to the isolated Asahigaoka village. Her new school has only five students including herself, all sharing a single classroom regardless of grade level. There are no convenience stores in the area, and it can take up to two hours for a bus to arrive. Nevertheless, Hotaru finds herself captivated by the countryside's charm thanks to her four unique schoolmates with whom she quickly forms a genuine bond. The most colorful of them is Renge Miyauchi, a first-grader who is often perceptive despite her age. However, no less intriguing are the three Koshigaya siblings: the quiet oldest brother Suguru, the petite older sister Komari, and the prankish youngest sister Natsumi. Having someone from the city join their cheerful little group enlivens the ordinary days in Asahigaoka. Not only does Hotaru bring firsthand knowledge from the alluring outside world, but her fresh outlook on life welcomes a blossom of change to their usual routine.